Pharmacology of Infectious Diseases & Immunizations for Advanced Practice Clinicians

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Pharmacology of Infectious Diseases & Immunizations for Advanced Practice Clinicians

Antimicrobials

• Drug classes
• Pharmacokinetic Properties
  • Concentration-dependent killing
  • Time-dependent killing
  • Post-antibiotic effect
• Common interactions with other drugs

Antibacterial Allergies – Sulfa and Penicillin

• Define true allergy
• Sulfonamide antibiotics vs non-antibiotics
• Penicillin – Cephalosporin cross-sensitivity

Bacteria

• Differentiation
• Normal flora
• Common pathogens

Antibacterial Resistance – Contributing Factors

• Trends
• Mechanisms of resistance
• Contributing factors

Methicillin-Resistant Staphylococcus Aureus – Community versus Hospital Acquired

• Differentiating between CA- and HA-MRSA
• Current clinical practice guidelines
• Pharmacologic management

Enterobacteriaceae Resistance

• Extended Spectrum Beta-Lactamase (ESBL)
  • What are ESBLs
  • Pharmacologic management
• Carbapenem-Resistant Enterobacteriaceae (CRE)
  • What are CREs
  • Pharmacologic management

Urinary Tract Infections

• Bacterial Etiology, Signs and Symptoms and Diagnosis
• Cystitis and pyelonephritis
• Complicated and uncomplicated
• UTIs in pregnancy
• Treatment (IDSA Guideline Treatment Algorithm)
  • Acute
  • Recurrent and relapse

Clostridium Difficile Infection

• Risk factors
• Pharmacology management
• Fecal Transplantation
• Probiotics literature review

Community–Acquired Pneumonia

• Bacterial etiology
• Diagnosis
• Typical vs. atypical
• Treatment (IDSA/ATS Guidelines) and monitoring
  • Outpatient vs. inpatient
  • Empiric treatment

Healthcare–Associated Pneumonia

• Bacterial etiology
• Treatment (IDSA/ATS Guidelines)

Upper Respiratory Tract Infections

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• Sinusitis and pharyngitis
  • Etiology (Viral vs. Bacterial)
  • Treatment

Skin and Soft Tissue Infections

• Cellulitis
• Bacterial etiology
  • Strep. vs. Staph. vs. MRSA
  • Signs & symptoms
  • Treatment (IDSA Guidelines)

Influenza

• Clinical features
• Diagnosis
• Pharmacology management

Immunizations (Adult)

• Types of Vaccines
• General recommendations
• Contraindications & precautions

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Watch this recording and learn proper prescribing, patient education and monitoring procedures for a variety of drug regimens used to treat common acute and chronic infectious diseases. Choosing an antibacterial agent can be challenging, given the plethora of drugs available on the market and the emerging trend in bacterial resistance.

You will learn the pharmacology of different classes of antimicrobials used to treat infectious disease states encountered in clinical practice. Discover the spectrums of activity, pharmacokinetic characteristics and parameters for monitoring therapeutic outcomes. Emphasis is placed on the new antimicrobials and advances in evidence-based treatment guidelines.

You will leave this recording better prepared to design appropriate and cost-effective drug regimens for improved therapeutic outcomes.

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